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Pathology Microbiology & Immunology
Columbia, SC 29208
(803) 733-3275
Fax: (803) 733-1515
E-mail: smartin@gw.med.sc.edu
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RESEARCH
The main research focus areas of the faculty in the
Department of Pathology and Microbiology are as follows.
CANCER
Immunology and
Immunotherapy
Interleukin-2 treatment of Melanoma
Complementary and Alternative Medicine
- Cannabinoids in the treatment of lymphoma (Nagarkatti,
P.,
Nagarkatti, M.,
McKallip)
- Dietary Supplements such as muscadine grapes, curcumin and
goldenseal, as well as exercise as immune potentiators (Mayer)
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Resveratrol as an anti-inflammatory agent (Nagarkatti,
P.,
Nagarkatti, M.,
Singh)
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Use of tea, gingko, ginseng for colon cancer (Wargovich)
Cell and Molecular Biology of Cancer
- Cervical Cancer – Role of TGFbeta/EGF receptors
in cancer progression (Creek,
Pirisi-Creek)
- Colon Cancer – Molecular mechanisms
underlying antioxidant properties of green tea
in cancer prevention and therapy; gene
expression signatures in carcinogenesis; role of
lipids in growth regulation (Wargovich,
Buckhaults,
Muga)
BIOLOGICAL AND CHEMICAL DEFENSE
VISION RESEARCH
- Retinal Pigment cells in Age-related Macular Degeneration
and Proliferative Vitreoretinopathy (Hunt,
M.,
Hunt, R.)
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Neovascularization in glaucoma (Tripathi)
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Proteomic approach to studies on anterior uveitis mediated
by muramyl peptides (Fox,
A;
Fox, K.)
DRUGS OF ABUSE
GENE REGULATION
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Alternative Splicing (Patton)
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Papilloma oncoproteins (Creek,
Pirisi-Creek)
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Loss of heterozygosity and tumor suppressor genes (Buckhaults)
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Arachidonic acid metabolites in carcinogenesis (Muga)
For
more information, please contact the Department at
(803)733-3275 or e-mail
smartin@gw.med.sc.ed
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